Try to execute RW Enhancer 2 as administrator mode or change the installation location of RW Enhancer 2.

This is perfectly normal. RW Enhancer 2 needs to be fully aware of your Train Simulator content so it need to load everything in the memory. (RAM)

Please make sure that you have started your scenario/quickdrive via the RW Enhancer 2 software and clicked on the “Drive Now”.
Or switch your display mode from “FullScreen” to “Borderless” in Train Simulator settings.

Please make sure that you have installed SAPI voices.

First try to perform a 'Reset' in the TS Content Cooker window inside RW Enhancer 2 if it still doesn't work, please go on RW Central forums (https://www.rwcentral.com/forum/157-bug-report/) and send us your 'debug.log' file. You can find it in the root directory of RW Enhancer 2.

We will update RW Enhancer 2 gradually over the next month to support more and more rolling stock

Please run “JoyToKey” with administrator mode under windows by opening right-click popup menu and select “Run as administrator”.